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Less potent, K10 adhesin [33]. Complementation of Newman DclfB with pCU1:clfB restored adherence to HLor (Figure S2). These data show that loricrin is a ligand for ClfB. To establish if ClfB alone can promote bacterial adhesion to immobilized loricrin, adhesion assays were performed using L. lactis MG1363 carrying a plasmid that expressed ClfB (pKS80:clfB) [40] and compared to L. lactis carrying t
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Iomedcentral.com/1471-2164/13/Page 8 ofFigure 4 AP-1 centered network of BaP-regulated genes sets. MetaCore Transcription Regulation algorithm with default settings was used for generation of biological networks. For clarity, only genes with direct connections with AP-1 and marked by the GO Process terms "Response to Stress" and "Response to Chemical Stimulus" are shown. The network objects were r
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Ns A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury. J Biol Chem 2000, 275:38848-38855. 7. Crowther JE, Kutala VK, Kuppusamy P, Ferguson JS, Beharka AA, Zweier JL, et al.: Pulmonary surfactant protein a inhibits macrophage reactive25.26.27.28.29.oxygen intermediate production in response to stimuli by reducing NADPH oxidase activity. J Immunol 2004, 172:
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630 genes, with 166 genes up-regulated and 464 genes down-regulated (Additional file 4). Genes involved in the xenobiotic defense system in vertebrates were part of the list, including biotransformation enzyme genes such as CYP2-like-11 gene (CBY24358), conjugating enzyme genes such as GSTa, and some ABC transporters and solute carrier proteins (Additional file 4). Superoxide dismutase and many AB
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Th Gag(p17)-E2 particles induced antigen-specific cytotoxic [65] CD8+ T cellsTh Gag(p17)-E2 particles induced antigen-specific cytotoxic [65] CD8+ T cells able to produce IFN- . Moreover, a moderate neutralizing antibody response was found in rabbits immunized with an E2 scaffold displaying a peptide [67] mimotope of the HIV-1 gp120 bridging sheet . Furthermore, E2 multimeric scaffolds displ
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Son by judgement or action in which his/her rights andSon by judgement or action in which his/her rights and dignity are disregarded. Prejudice leads to action, and this action is to stigmatise. Stigma is a brand. To brand is to mark indelibly as a sign of quality. To brand is also to impress indelibly on one's memory, therefore the stigma is both in the stigmatised person and in the stigmat
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11:156-160)Schizophrenia and most other forms of serious mental illness have11:156-160)Schizophrenia and most other forms of serious mental illness have traditionally been viewed as chronic conditions with poor outcomes. This pessimistic view has begun to change, as a series of long-term outcome studies have demonstrated that the course is more variable both across and within individuals, an
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S also measured. The KD measured for GST-Fga316?67 was 5.25 mM, in the same low mM range as the other ligands. This indicates that ClfB has a similar affinity for loricrin, K10 and the aC-region of Fg. SPR was also used to identify binding sites within human loricrin. Loricrin is composed of three Gly-Ser-rich regions capable of forming omega loops (Figure S3) [37]. Regions 2 andFigure 1. ClfB pro

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